SELZENTRY is an anti-HIV medicine called a CCR5 antagonist. HIV-1 (Human Immunodeficiency Virus) is the virus that causes AIDS (Acquired Immune Deficiency Syndrome).
SELZENTRY is used with other anti-HIV medicines in adults with CCR5-tropic HIV-1 infection.
Use of SELZENTRY is not recommended in people with dual/mixed or CXCR4-tropic HIV-1.
SELZENTRY has not been studied in children less than 16 years of age.
SELZENTRY does not cure HIV-1 infection and you may continue to experience illnesses associated with HIV-1 infection, including opportunistic infections. You should remain under the care of a doctor when using SELZENTRY.
Avoid doing things that can spread HIV-1 infection
HIV-1 enters cells in your blood by attaching itself to structures on the surface of the cell called receptors. SELZENTRY blocks a specific receptor called CCR5 that CCR5-tropic HIV-1 uses to enter CD4 or T-cells in your blood. Your healthcare provider will do a blood test to see if you have been infected with CCR5-tropic HIV-1 before prescribing SELZENTRY for you.
SELZENTRY does not work in all people with CCR5-tropic HIV-1 infection.
People with severe kidney problems or who are on haemodialysis and are taking certain other medications should not take SELZENTRY. Talk to your healthcare provider before taking this medicine if you have kidney problems.
Before you take SELZENTRY, tell your healthcare provider if you:
Antiretroviral Pregnancy Registry. There is a pregnancy registry for women who take antiviral medicines during pregnancy. The purpose of the registry is to collect information about the health of you and your baby. Talk to your healthcare provider about how you can take part in this registry.
Do not take products that contain St. John’s wort (Hypericum perforatum). St. John’s wort may lower the levels of SELZENTRY in your blood so that it will not work to treat your CCR5-tropic HIV-1 infection.
Know the medicines you take. Keep a list of your medicines. Show the list to your healthcare provider and pharmacist when you get a new medicine.
Take SELZENTRY exactly as prescribed by your healthcare provider. SELZENTRY comes in 150-mg and 300-mg tablets. Your healthcare provider will prescribe the dose that is right for you.
Do not change your dose or stop taking SELZENTRY or your other anti-HIV medicines without first talking with your healthcare provider.
There have been serious side effects when SELZENTRY has been given with other anti-HIV drugs including:
The most common side effects of SELZENTRY include colds, cough, fever, rash, and dizziness.
Tell your healthcare provider about any side effect that bothers you or does not go away.
These are not all of the side effects with SELZENTRY. For more information, ask your healthcare provider or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep SELZENTRY and all medicines out of the reach of children.
Medicines are sometimes prescribed for conditions that are not mentioned in Medication Guides. Do not use SELZENTRY for a condition for which it was not prescribed. Do not give SELZENTRY to other people, even if they have the same symptoms you have. It may harm them.
This Medication Guide summarizes the most important information about SELZENTRY. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for more information about SELZENTRY that is written for health professionals. For more information, go to www.selzentry.com.
The brands listed are the trademarks or registered marks of their respective owners and are not trademarks of ViiV Healthcare. The makers of these brands are not affiliated with and do not endorse ViiV Healthcare or its products.
This Medication Guide has been approved by the US Food and Drug Administration.
Tell your healthcare provider if you have vomiting, diarrhea, or signs of dehydration that does not go away. SELZENTRY may cause fertility problems in males and females, which may affect your ability to have a child.
Talk to your healthcare provider if this is a concern for you. These are not all of the possible side effects of SELZENTRY. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Ask your healthcare provider if you do not know.