KYMRIAHTM (KIM-RYE-AH) (Tisagenlecleucel)

KYMRIAHTM
(KIM-RYE-AH)
(Tisagenlecleucel)

Chemotherapy

KYMRIAHTM
(KIM-RYE-AH)
(Tisagenlecleucel)

Chemotherapy

What is KYMRIAHTM (Tisagenlecleucel)?

KYMRIAH is made from your own white blood cells and is a prescription cancer treatment used in patients up to 25 years old who have acute lymphoblastic leukemia (ALL) that is either relapsing (went into remission, then came back) or refractory (did not go into remission after receiving other leukemia treatments). It is also used in patients with non- Hodgkin lymphoma that has relapsed or is refractory after having at least two other kinds of treatment

What is the most important information I should know about KYMRIAH?

AFINITOR can cause serious side effects. These serious side effects include:

KYMRIAH can increase the risk of life-threatening infections that may lead to death. Tell your healthcare provider right away if you develop fever, chills, or any signs or symptoms of an infection
KYMRIAH can lower one or more types of your blood cells (red blood cells, white blood cells, or platelets). After treatment, your healthcare provider will test your blood to check for this. Tell your healthcare provider right away if you get a fever, are feeling tired, or have bruising or bleeding.
Having KYMRIAH in your blood may cause a false-positive HIV test result by some commercial tests.

How should I take KYMRIAH?

Since KYMRIAH is made from your own white blood cells, your healthcare provider has to take some of your blood. This is called “leukapheresis.” It takes 3 to 6 hours and may need to be repeated. A tube (intravenous catheter) will be placed in your vein to collect your blood
Your blood cells are frozen and sent to the manufacturing site to make KYMRIAH. It takes about 3-4 weeks from the time your cells are received at the manufacturing site and shipped back to your health care provider, but the time may vary.
Before you get KYMRIAH, your healthcare provider may give you chemotherapy for a few days to prepare your body.
When your body is ready, your healthcare provider will give you KYMRIAH through a tube (intravenous catheter) in your vein. This usually takes less than one hour.
You should plan to stay within 2 hours of the location where you received your treatment for at least 4 weeks after getting KYMRIAH. Your healthcare provider will check to see if your treatment is working and help you with any side effects that occur

Important Safety Information

Ask your healthcare provider if you do not know.

What should I tell my healthcare provider before taking KYMRIAH?

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It is important that you tell your health care providers that you have received KYMRIAH. Your healthcare providers may give you other medicines to treat your side effects.
Tell your healthcare provider right away if you develop fever, chills, or any signs or symptoms of an infection
After treatment, your healthcare provider will test your blood to check for this. Tell your healthcare provider right away if you get a fever, are feeling tired, or have bruising or bleeding.

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General information about KYMRIAH

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use KYMRIAH for a condition for which it was not prescribed. Talk to your healthcare provider about any concerns. You can ask your healthcare provider for information about KYMRIAH that is written for healthcare professionals

What are the ingredients in KYMRIAH?

Active ingredient: Tisagenlecleucel

Other ingredient:

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