Niraparib (Zejula)

What is Niraparib ( Zejula)?

Niraparib is the generic name for the trade name drug ZejulaTM. In some cases, health care professionals may use the trade name ZejulaTM when referring to the generic drug name Niraparib.

Niraparib is Used For?

Niraparib is used to help maintain the response of certain types of ovarian (female reproductive organs where eggs are formed), fallopian tube (tube that transports eggs released by the ovaries to the uterus), and peritoneal (layer of tissue that lines the stomach) cancer in people who have completely responded or partially responded to other chemotherapy medication(s). It is also used to treat certain types of ovarian, fallopian tube, or peritoneal cancer when the cancer has gotten worse after 3 or more chemotherapy treatments. Niraparib is in a class of medications called poly (ADP-ribose) polymerase (PARP) inhibitors. It works by killing cancer cells.

How Should This Medicine Be Used?

Niraparib comes as a capsule to take by mouth once daily. Take Niraparib at around the same time every day with or without food. If you experience nausea after taking Niraparib, take it once daily at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Niraparib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the capsules whole; do not open, chew, or dissolve them.

If you vomit after taking Niraparib, do not take another dose. Continue your regular dosing schedule.

Your doctor may decrease your dose of Niraparib, or permanently or temporarily stop your treatment, if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with Niraparib.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

What are the Niraparib Side Effects?

Important things to remember about the side effects of Niraparib:

  • Most people will not experience all of the Niraparib side effects listed.
  • Side effects are often predictable in terms of their onset, duration, and severity.
  • There are many options to help minimize or prevent side effects.
  • There is no relationship between the presence or severity of side effects and the effectiveness of the medication.

The following side effects are common (occurring in greater than 30%) for patients taking Niraparib:

  • Nausea
  • Decreased platelet count
  • Fatigue (including weakness)
  • Anemia (low red blood cell count)
  • Constipation
  • Vomiting
  • Decreased neutrophil count (white blood cells that fight infection)
  • Increased liver function test: AST and/or ALT

These are less common side effects (occurring in 10-29%) for patients receiving Niraparib:

 

  • Insomnia (sleep disturbance)
  • Headache
  • Decreased appetite
  • Nasopharyngitis (Irritated nose or throat)
  • Skin rash
  • Mouth sores
  • Hypertension (high blood pressure)
  • Dizziness
  • Heartburn
  • Back pain
  • Low total white blood cell count
  • Cough
  • Urinary tract infections
  • Anxiety

Note all side effects are listed above. Side effects that are very rare — occurring in less than about 10 percent of patients — are not listed here.

 

Always inform your health care provider if you experience any unusual symptoms.

What Other Information Should I Know?

Keep all appointments with your doctor and the laboratory. Your doctor will check your blood pressure regularly and order certain lab tests before and during your treatment to check your body’s response to niraparib.

In some cases, niraparib may only be used in people with a certain genetic make-up. Your doctor may order a blood test to help decide if this medication is right for you.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

General Facts & FAQ

Zejula Medical Fact
Zejula (Niraparib 100 mg.) is indicated for Maintenance treatment in adults patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy

  • What is the generic name of Zejula?
    The generic name of Zejula is Niraparib.
  • Who is the manufacturer of Zejula?
    Zejula is manufactured by Tesaro, Inc.
  • Is Zejula approved by USA FDA?
    Yes, Zejula is approved by FDA. The product was approved in 2017
  • What is the dosage form of Zejula?
    Zejula is available as 100 mg Capsules
  • Prescribing information of Zejula?
    Click Here to download full prescribing information.

What are the storage conditions of Zejula (Niraparib 100 mg)?
The product must be kept at Room Temperature. The product should be Stored at 20° to 25°C (68° to 77°F). Excursions are permitted between 15°C to 30°C (59°F to 86°F)

 

How Zejula (Niraparib 100 mg) capsule is supplied?
Each capsule of Zejula contains 100 mg of Niraparib. Each Bottle contains 90 Capsules.

 

How does Zejula work?
The active substance in Zejula, niraparib, blocks the action of enzymes called PARP-1 and PARP-2, which help to repair damaged DNA in cells when the cells divide to make new cells. By blocking PARP enzymes, the damaged DNA in cancer cells cannot be repaired, and, as a result, the cancer cells die.

 

About Zejula (Niraparib 100 mg) Medicine.
Zejula – Niraparib 100 mg. is supplied for Tenders, Emergency imports, Orphan drug, Reference listed drugs, Comparator Drug, Name patient medicine and Innovator samples etc.

 

What is Zejula (Niraparib 100 mg) used for?
Zejula (Niraparib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Zejula is used as a “maintenance” treatment to keep certain types of cancer from coming back.

 

How many brands of Zejula (Niraparib 100 mg) are available in India?
Zejula (Niraparib 100 mg) is an innovator brand. Zejula or any other generic of
Niraparib 100 mg is not available in India

 

Is there any generic or bio similar available for Zejula (Niraparib 100 mg.)
There is no generic or bio similar available for Zejula (Niraparib 100 mg.) anywhere in the world.

 

What is the price of Zejula in India?
You can call or WhatsApp +91-882-688-3200 or send mail to shasi@mozocare.com.com to know the cost

 

What is price of Zejula?
You can call /at whats app +91-882-688-3200 or send mail to shasi@mozocare.com.in know the price.

 

Other information about Zejula
The European Commission granted a marketing authorization valid throughout the European Union for Zejula on 16 November 2017.

 

Is it safe to buy Zejula in India from local distributor?
It is always better to check the credential of the person / distributor before confirming.
As per the legal guidelines, only patients can import the product after getting proper Documentation.

 

Patients must check following documents before importing Zejula?

  • How the product entered in India
  • How is the packaging
  • Courier / Shipping Details
  • Verification of the foreign supplier e.g. drugs license and government approval of the ware house etc.
  • Import documents
  • Bill of entry of custom department
  • Please do not buy Zejula (Niraparib) where cash payment in involved

 

What documents are required to import Zejula (Niraparib 100 mg) to India?
Zejula (Niraparib 100 mg) can be imported by patients or government hospital on the name of the patients only

The following documentation required to import the product:

  • Valid prescription from a qualified doctor.
  • Patients diagnostic reports
  • Patients id proof (issued by government of India)

 

Is Zejula available in India?
Zejula is not available or approved by drug authorities in India. However patients can access the product by getting import permission from government of India*

Mozocare helps import of cancer medicines on the named patient supply (NPS). Mozocare is facilitator and provide input on

  • Availability in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc.)
  • Medicine Price.
  • Finding Genuine and reliable source from Canada, Europe, USA and Australia
  • Ensuring 100% transparency.

Zejula (Niraparib 100 mg) can be made available to patients, doctors and hospitals at Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after the receipt of valid prescription of doctor and import permit.

 

About Mozocare

Mozocare is a medical access platform for hospitals and clinics to assist patients to access the best medical care at affordable prices. It offers medical information, medical treatment, pharmaceuticals, medical equipment, laboratory consumables, and other allied services.

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