What is BEVYXXA ?

Bevyxxa (betrixaban) blocks the activity of certain clotting substances in the blood.

Bevyxxa is a prescription medicine used to prevent blood clots in adults who have a serious illness and decreased ability to move. Blood clots are more likely when you are bedridden and you cannot move around.

BEVYXXA is Uses For?

Anagrelide is used to treat a certain blood disorder (thrombocythemia), which is caused by your bone marrow making too many platelets. Platelets are a blood cell that the body uses to form blood clots. Too many platelets can cause problems with your circulation, including unwanted blood clots and bleeding problems. This drug reduces the number of platelets in the bloodstream by blocking their production.

Medical Condition Before Taking Agrylin?

You should not use Bevyxxa if you are allergic to betrixaban, or if you have active or uncontrolled bleeding.

Bevyxxa may cause you to bleed more easily, especially if you have kidney disease or you use other medicines such as:

  • medicines to treat or prevent blood clots;
  • certain antidepressantsantibiotics, antifungal medicines, HIV medicines, or heart rhythm medicines; or
  • aspirin or an NSAID (nonsteroidal anti-inflammatory drug) such as ibuprofen (AdvilMotrin), naproxen (Aleve), celecoxibdiclofenacindomethacin, or meloxicam.

Bevyxxa can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:

  • you have a genetic spinal defect;
  • you have a spinal catheter in place or if a catheter has been recently removed;
  • you have had spinal surgery, or repeated spinal taps or epidural anesthesia; or
  • you take an NSAID, or use other medicines to treat or prevent blood clots.

To make sure Bevyxxa is safe for you, tell your doctor if you have ever had:

  • liver or kidney disease;
  • an artificial heart valve; or
  • a bleeding or blood clotting disorder.


It is not known whether this medicine will harm an unborn baby. However, taking this medicine during pregnancy may increase the risk of bleeding while you are pregnant or during your delivery. Tell your doctor if you are pregnant or plan to become pregnant.


What are the Bevyxxa Side Effects?

Along with its needed effects, betrixaban (the active ingredient contained in Bevyxxa) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking betrixaban:

More common

Less common

  • Bladder pain
  • bloody or cloudy urine
  • blurred vision
  • convulsions
  • decreased urine
  • difficult, burning, or painful urination
  • dizziness
  • dry mouth
  • frequent urge to urinate
  • headache
  • increased thirst
  • irregular heartbeat
  • loss of appetite
  • lower back or side pain
  • mood changes
  • muscle pain or cramps
  • nausea or vomiting
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • pounding in the ears
  • unusual tiredness or weakness

Some side effects of betrixaban may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Incidence not known

  • Fever
  • joint or muscle pain
  • redness and soreness of the eyes
  • skin rash
  • sores in the mouth
  • stomach pain
  • swelling of the feet or lower legs


The recommended dose of BEVYXXA is an initial single dose of 160 mg, followed by 80 mg once daily. Daily oral doses should be given at the same time of day with food.

The recommended duration of treatment is 35 to 42 days.

Severe Renal Impairment

For patients with severe renal impairment (CrCl ≥ 15 to < 30 mL/min computed by Cockcroft-Gault using actual body weight) the recommended dose of BEVYXXA is an initial single dose of 80 mg followed by 40 mg once daily [see WARNINGS AND PRECAUTIONSUse In Specific PopulationsCLINICAL PHARMACOLOGY]. The recommended duration of treatment is 35 to 42 days.

Use With P-Gp Inhibitors

For patients receiving or starting concomitant P-gp inhibitors the recommended dose of BEVYXXA is an initial single dose of 80 mg followed by 40 mg once daily [see WARNINGS AND PRECAUTIONSDRUG INTERACTIONSCLINICAL PHARMACOLOGY]. The recommended duration of treatment is 35 to 42 days.

Missed Dose

If a dose of BEVYXXA is not taken at the scheduled time, the dose should be taken as soon as possible on the same day. The BEVYXXA dose should not be doubled to make up for a missed dose.

General Facts & FAQ

What is the Generic Name for the trade name drug BEVYXXA® ?

Betrixaban is Generic Name for the trade name drug BEVYXXA®

What is the Manufacturer Name of BEVYXXA®?

BEVYXXA® is manufactured by Portola Pharmaceuticals.

Is BEVYXXA® approved by FDA?

Yes, BEVYXXA® is approved by FDA. Date of approval: 2017

What is the dosage and form of BEVYXXA® is available?

BEVYXXA® is available as capsules of 40mg and 80mg.

What is the Highlights of prescribing information of BEVYXXA®?

Click Here to download full prescribing information.

About Mozocare

Mozocare is a medical access platform for hospitals and clinics to assist patients to access the best medical care at affordable prices. It offers medical information, medical treatment, pharmaceuticals, medical equipment, laboratory consumables, and other allied services.

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